Projects per year
Personal profile
SUMMARY of research interests (100 words)
Dr Broughton's research interests lie in the mechanisms of ageing, particularly the relationship between lifespan and healthspan, using the fruit fly, Drosophila melanogaster, as a model organism.
She has a particular interest in the role of the insulin/IGF-like signalling pathway and diet in modulating lifespan and age-related functional and cognitive decline using behavioural and anatomical measures of brain ageing.
Profile
Qualifications
BSc (Hons) Biological Sciences from Leicester University (1987)
PhD from New York University (2002)
Personal Introduction
My research interests lie in the mechanisms of ageing using the fruit fly, Drosophila melanogaster, as a model organism. I have a particular interest in the role of the insulin/IGF-like signalling pathway in modulating lifespan and age-related functional decline.
Current Teaching
BIOL 113 Genetics
BIOL 311 Genetics
BIOL 332 Neurobiology
BIOL 364 Ageing
Keywords
- Biological Sciences
- Biomedical and life sciences
User-defined keywords
- Ageing
- Insulin/IGF-like signalling
- Drosophila melanogaster
- Functional senescence
- brain ageing
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 5 Finished
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Securing Better Health, Ageing, and Wellbeing
Broughton, S. (Principal Investigator)
15/08/23 → 30/08/25
Project: Research
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Harnessing knowledge of lifespan biological, health, environmental and psychosocial mechanisms of cognitive frailty for integrated interventions
Broughton, S. (Co-Investigator) & Holland, C. (Principal Investigator)
14/02/22 → 30/04/25
Project: Research
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Harnessing knowledge of lifespan biological, health, environmental and psychosocial mechanisms of cognitive frailty for integrated interventions
Broughton, S. (Co-Investigator) & Holland, C. (Principal Investigator)
14/02/22 → 31/03/25
Project: Research
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Investigating the Biological Mechanisms of Brain Ageing
Broughton, S. (Principal Investigator)
1/11/19 → 31/03/22
Project: Research
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Biology of Ageing - Sir John Fisher Foundation Studentship (Year 3)
Broughton, S. (Principal Investigator)
1/10/18 → 30/09/19
Project: Research
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Interventions for Cognitive Frailty: developing a Delphi consensus with multidisciplinary and multisectoral experts
Holland, C., Dravecz, N., Broughton, S., Barker, L., Bature, F., Clarke, C., Danat, I. M., Das, S., Dias, I. H. K., Dawson, A., Dixon, M., Ellison, A., Façal, D., Finch, R., Gaffney, C., Gow, A. J., Kelaiditi, E., Klimczuk, A., Navarro-Pardo, E. & Sharratt, P. & 5 others, , 4/06/2025, In: Frontiers in Aging Neuroscience. 17, 1541048.Research output: Contribution to Journal/Magazine › Journal article › peer-review
Open Access -
Disruption of tRNA biogenesis enhances proteostatic resilience, improves later-life health, and promotes longevity
Malik, Y., Kulaberoglu, Y., Anver, S., Javidnia, S., Borland, G., Rivera, R., Cranwell, S., Medelbekova, D., Svermova, T., Thomson, J., Broughton, S., von der Haar, T., Selman, C., Tullet, J. M. A. & Alic, N., 22/10/2024, In: Plos Biology. 22, 10, e3002853.Research output: Contribution to Journal/Magazine › Journal article › peer-review
Open Access -
INTERVENTIONS FOR COGNITIVE FRAILTY: DELPHI CONSENSUS WITH RESEARCHERS, CLINICIANS, AND EXPERTS BY EXPERIENCE
Holland, C., Dravecz, N., Broughton, S., Davis, S. F. & Dixon, M., 31/12/2024, In: Innovation in Aging. 8, Supplement 1, p. 364-364 1 p.Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review
Open Access -
Understanding exogenous factors and biological mechanisms for cognitive frailty: A multidisciplinary scoping review
Holland, C., Dravecz, N., Owens, L., Benedetto, A., Dias, I., Gow, A. & Broughton, S., 30/11/2024, In: Ageing Research Reviews. 101, 102461.Research output: Contribution to Journal/Magazine › Review article › peer-review
Open Access -
Editorial: Model organisms in aging research: Drosophila melanogaster
Clancy, D., Chtarbanova, S. & Broughton, S., 10/01/2023, In: Frontiers in Aging. 3, 1118299.Research output: Contribution to Journal/Magazine › Editorial › peer-review
Open Access
Activities
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British Neuroscience Association (BNA) Training Academy Event.
Dawson, N. (Organiser), Benedetto, A. (Speaker), Broughton, S. (Speaker), Hawkes, C. (Speaker), Brennan, C. (Speaker) & Willaime-Morawek, S. (Speaker)
5/11/2025Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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SAAgeNet Grant Sandpit Event
Broughton, S. (Organiser)
9/07/2025 → 10/07/2025Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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4th SAAgeNet Conference
Broughton, S. (Organiser)
10/03/2025 → 11/03/2025Activity: Participating in or organising an event types › Participation in conference - Academic
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CFIN Policy Event
Broughton, S. (Organiser)
11/02/2025Activity: Participating in or organising an event types › Participation in conference -Mixed Audience
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Centre for Ageing Research Annual Showcase
Broughton, S. (Speaker)
11/12/2024Activity: Talk or presentation types › Oral presentation