Projects per year
Personal profile
SUMMARY of research interests (100 words)
In my research I study how interactions between animals and microbes work and evolve, how they influence each other’s health and the conditions that lead to disease. I do this by using the nematode model Caenorhabditis elegans and its naturally associated bacteria, as well as bacterial pathogens that cause infection. To understand host-microbe interactions I combine multiomics (transcriptomics, proteomics and targeted metabolomics) with genetic (mutants, RNAi) and phenotypic (microscopy, survival, bacterial load, fitness) analyses. I am currently working on the research grant (BBSRC: BB/S017127/1) awarded to Dr. Alex Benedetto to map the genetic network that governs worm gut-bacteria interactions.
Keywords
- Biomedical and life sciences
- Evolutionary inmmunology
- Innate immunity
- Host-microbe interactions
- Microbiota
- Host-pathogen interctions
- Infection
- C. elegans
- Gene regulation
- Metabolism
Collaborations and top research areas from the last five years
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Brazil-UK Partnership: New Bioactives for a Healthy Gut, targeting the gut microbiota
Benedetto, A. (Principal Investigator) & Zarate Potes, A. (Co-Investigator)
1/06/22 → 31/05/26
Project: Research
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Integrated Multiomics of Host-bacteria Interactions during C. elegans Gut Infections
Zarate Potes, A. (Senior Research Associate)
Project: Research
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Resolving the ‘dual-extraction bottleneck’ in transcriptomics for a deep understanding of host-microbe interactions
Zarate Potes, A. (Principal Investigator)
29/11/21 → 29/11/22
Project: Research
Research output
- 10 Journal article
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Unanticipated specificity in effector-triggered immunity
Zárate-Potes, A., Schulenburg, H. & Dierking, K., 15/11/2024, (E-pub ahead of print) In: Trends in Immunology.Research output: Contribution to Journal/Magazine › Journal article › peer-review
Open Access -
High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health
Ali, I., Martin, J., Zárate-Potes, A. & Benedetto, A., 28/04/2022, In: Journal of Visualized Experiments. 2022, 182, e63860.Research output: Contribution to Journal/Magazine › Journal article › peer-review
Open AccessFile53 Downloads (Pure) -
Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions
Zárate-Potes, A., Ali, I., Ribeiro Camacho, M., Brownless, H. & Benedetto, A., 10/05/2022, In: Frontiers in Microbiology. 13, 17 p., 853629.Research output: Contribution to Journal/Magazine › Journal article › peer-review
Open AccessFile49 Downloads (Pure) -
Effector and regulator: Diverse functions of C. elegans C-type lectin-like domain proteins
Pees, B., Yang, W., Kloock, A., Petersen, C., Peters, L., Fan, L., Friedrichsen, M., Butze, S., Zárate-Potes, A., Schulenburg, H. & Dierking, K., 1/04/2021, In: PLoS Pathogens. 17, 4, 25 p., e1009454.Research output: Contribution to Journal/Magazine › Journal article › peer-review
Open Access5 Citations (Scopus) -
Guard proteins keep watch at epithelial walls
Zárate-Potes, A. & Dierking, K., 13/07/2021, In: Immunity. 54, 7, p. 1366-1368 3 p.Research output: Contribution to Journal/Magazine › Journal article › peer-review
Open AccessFile25 Downloads (Pure)
Activities
- 1 Other
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FURNESS STEM SHOW 2023
Jackson-Jones, L. (Organiser), Allinson, S. (Organiser), Shih, B. (Presenter), Hammond, J. (Contributor), Zarate Potes, A. (Presenter), Weight, C. (Presenter), Hardgrave, A. (Presenter), Barnes, C. (Presenter), Dewar, C. (Presenter), Macharia, S. (Presenter), Iqbal, N. (Presenter), Fielding, A. (Presenter) & Urbaniak, M. (Contributor)
14/03/2023 → 15/03/2023Activity: Participating in or organising an event types › Other
Press/Media
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Prosper’s Second Cohort Celebrates End of Year
24/02/23
1 Media contribution
Press/Media: Newspaper Article