Alejandra Zarate Potes
20152024

Research activity per year

Personal profile

SUMMARY of research interests (100 words)

In my research I study how interactions between animals and microbes work and evolve, how they influence each other’s health and the conditions that lead to disease. I do this by using the nematode model Caenorhabditis elegans and its naturally associated bacteria, as well as bacterial pathogens that cause infection. To understand host-microbe interactions I combine multiomics (transcriptomics, proteomics and targeted metabolomics) with genetic (mutants, RNAi) and phenotypic (microscopy, survival, bacterial load, fitness) analyses. I am currently working on the research grant (BBSRC: BB/S017127/1) awarded to Dr. Alex Benedetto to map the genetic network that governs worm gut-bacteria interactions.

Keywords

  • Biomedical and life sciences
  • Evolutionary inmmunology
  • Innate immunity
  • Host-microbe interactions
  • Microbiota
  • Host-pathogen interctions
  • Infection
  • C. elegans
  • Gene regulation
  • Metabolism

Collaborations and top research areas from the last five years

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